Know Your Risk. Reclaim Your Future.
The single most important piece of information for your brain health journey is now available as a simple, at-home test. As a 30-year dementia specialist, this is the one test I believe every Boomer should consider.
Affiliate disclosure: I may earn a commission if you purchase through this link.
Your Genes Are Not Your Destiny. But Knowing Them Is Your Power.
For decades, the world of genetics felt distant and inaccessible. Today, understanding your unique genetic blueprint for brain health is as simple as a test you can take from your own kitchen counter. The APOE gene is the most-studied and most significant genetic risk factor for late-onset Alzheimer's disease.
Knowing your APOE4 status is the starting gun for a proactive, empowered approach to your brain health. It's not about fear — it's about focus. It's the first step on The Silver Path.
"For 30 years, I've worked with families navigating the challenges of dementia. Seeing my own genetic risk in black and white wasn't scary — it was clarifying. It was the catalyst that solidified every principle I now teach. I don't just recommend this test; I live by the information it gave me. It's the first door to walk through on The Silver Path."
30-year dementia specialist. Biohacker. Aging backwards at 70. Helping Boomers outsmart their genes and reclaim their brain health.
Get the Test I RecommendYour Path to Clarity in Three Simple Steps
Order Your Kit
Securely order your empowerDX APOE Gene Test. It will be delivered discreetly to your doorstep anywhere in the US.
Simple At-Home Sample
Follow the easy instructions to collect a simple cheek swab. No needles, no clinics, no appointments. Mail it back in the pre-paid mailer.
Receive Your Results
Within a few weeks, access your results through a secure online portal. Your information is private, protected, and yours alone.
Your Results Are a Roadmap, Not a Verdict.
Receiving your APOE4 status is the beginning of a conversation, not the end. It's the data you need to build a truly personalized brain health strategy. This is where the real work — and the real hope — begins.
This is the first step in the journey we walk together in the Hack Your APOE4 program, where we turn this knowledge into a concrete, day-by-day plan to outsmart your genes.
Explore Hack Your APOE4What You'll Understand After Your Results:
The Gene Your Doctor Probably Never Tested.
Once you know your APOE4 status, the MTHFR Methylation Gene Test is the natural next step — and empowerDX's #1 best seller for good reason.
MTHFR Methylation Gene Test
The MTHFR gene controls how your body processes B vitamins — directly affecting homocysteine levels, a key marker for brain aging and Alzheimer's risk. APOE4 and MTHFR variants often work together, making this the essential companion test to your APOE4 results.
Get the MTHFR Gene TestAffiliate disclosure: I may earn a commission if you purchase through this link.
Why MTHFR Matters for Brain Health:
Two More Tests Every APOE4 Carrier Should Know.
These two deficiencies are epidemic in Boomers and directly accelerate the exact brain aging pathways that APOE4 makes you vulnerable to.
Vitamin D Test
Over 70% of older adults are deficient in Vitamin D — and low levels are directly linked to cognitive decline, depression, and increased Alzheimer's risk. For APOE4 carriers, optimizing Vitamin D is one of the most actionable and affordable steps you can take.
Get the Vitamin D TestVitamin B12 + Folate (B9) Test
B12 and Folate are the two nutrients most critical for protecting your brain from homocysteine damage — the same pathway affected by MTHFR variants. This test pairs perfectly with your MTHFR results to create a complete, actionable picture of your brain health status.
Get the B12 + Folate TestInflammation (hs-CRP) Test
Chronic low-grade inflammation is one of the biggest accelerators of brain aging — and APOE4 carriers are especially vulnerable to its effects. The hs-CRP test measures your body's inflammation level so you can take targeted action before it silently damages your brain.
Get the Inflammation TestAffiliate disclosure: I may earn a commission if you purchase through these links.
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CLIA-Certified Labs
Testing performed in highly-regulated, clinical-grade laboratories ensuring accuracy and reliability.
Physician-Ordered
A licensed physician reviews and orders every test, adding a critical layer of clinical oversight.
Privacy-Focused
Your genetic data is your own. empowerDX is committed to secure and confidential testing practices.
Real People. Real Results.
“I finally stopped being afraid of my family history. Getting that test result was the best thing I ever did — it gave me a plan instead of just worry.”
— Margaret, 68
APOE4 carrier · Now following the Hack Your APOE4 protocol
“I ordered it on a Tuesday, had my results by Friday. I cried a little — then I called Jess. She turned my fear into the most empowering conversation of my life.”
— Robert, 72
Retired teacher · San Diego, CA
“My doctor had never even mentioned APOE4 testing. I did it myself, brought the results in, and suddenly we were having a completely different conversation about my brain health.”
— Carol, 65
APOE4/3 carrier · Now working on her CALM Home
“At 70, I thought it was too late to do anything. Jess showed me it's absolutely not. The test was just the beginning — I feel more in control of my health than I did at 50.”
— Patricia, 70
Grandmother of 4 · Portland, OR
“My husband and I both took the test. We're not APOE4 carriers — but knowing that? Priceless peace of mind. We still followed the lifestyle recommendations anyway!”
— Susan & Dave, 66 & 69
Retired couple · Scottsdale, AZ
“I was the skeptic in the family. My daughter practically dragged me to this page. Best $189 I ever spent. I have my MTHFR results back too now and I finally understand my body.”
— Frank, 74
Retired engineer · Chicago, IL
The Questions Every Boomer Asks First.
Q.What do I do after I get my results?
This is exactly what the Hack Your APOE4 program is built for. Your results are just the starting point — the program walks you through a concrete, day-by-day plan to reduce your risk, protect your brain, and age backwards. Whether you carry one copy, two copies, or none, there are powerful steps you can take right now.
Start the Hack Your APOE4 Program →Q.What if my results show I have the APOE4 gene?
Take a breath — this is not a diagnosis. It's information. And information is power. APOE4 carriers who take action early have the best outcomes. The Hack Your APOE4 program was specifically designed for carriers who want to outsmart their genes with science-backed strategies for sleep, nutrition, movement, stress, and environment.
See What's Possible in the Program →Q.Will knowing my APOE4 status make me anxious?
For most people, knowing is actually a relief — it replaces vague fear with a clear plan. Jess has guided hundreds of people through their results over 30 years. The Hack Your APOE4 program includes a full 'What Your Results Mean' module designed to turn any anxiety into empowered action.
Get the Support You Need in the Program →Q.Is this test accurate? Can I trust an at-home test?
Yes. empowerDX uses CLIA-certified laboratories — the same standard as your doctor's office. The APOE gene test is a simple cheek swab with a finger prick, processed in a certified lab, with results reviewed by a physician. It's the same test your doctor would order, just without the waiting room.
Q.What if I don't carry APOE4 — is the test still worth it?
Absolutely. Knowing you don't carry APOE4 is valuable peace of mind — and the brain-healthy lifestyle strategies in the Hack Your APOE4 program benefit everyone, regardless of genetic status. Many non-carriers join the program simply because the strategies are that good.
Explore the Program Anyway →Q.How long does it take to get results?
Most people receive their results within 5–7 business days after the lab receives their sample. You'll get a secure online report with a physician-reviewed guide explaining what your results mean.
Free Guide
Get My Free Guide:
Your APOE4 Results — 5 Things to Do Right Now
A 9-page, beautifully designed guide from a 30-year dementia specialist — turning your genetic results into a clear, actionable path forward.
Soooo You Got Your Results, Huh? Just a 2 or 3... Whew. 😅
Nothin' to see here... 🚫 THINK AGAIN.
Here's what your doctor probably didn't tell you: if you spent your 70s, 80s, and 90s working hard, playing hard, and living life at full speed — your lifestyle may have created a brain health risk that has nothing to do with APOE4. Insulin resistance, high homocysteine, and chronic inflammation drive dementia through a completely separate pathway. And that pathway hits APOE2 and APOE3 carriers just as hard.
Homocysteine Blood Test
~$40 · Life Extension · At-Home
High homocysteine silently damages brain blood vessels. One of the most underdiagnosed risk factors — and completely correctable with B vitamins.
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Glucose & Insulin Resistance
From $15 (lab) · Or try Lingo CGM (real-time)
Insulin resistance is now called "Type 3 Diabetes" by researchers — because chronically high blood sugar starves the brain of energy. Don't run from this one.
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Don't run — we got you. It can all be done from home. 🤣
See Your Full Results Action PlanKnow someone who should get tested?
1 in 5 people carry APOE4 — most don't know it. Share this page and help someone you love take control of their brain health.
There Is No More Powerful Investment Than Understanding Your Own Biology.
This test is more than just data. It's the key that unlocks a proactive, empowered, and hopeful path forward on The Silver Path.